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Studies have shown that the peptide demonstrates approximately 40% oral bioavailability in animal models and exhibits rapid metabolism with a serum half-life of approximately 4 minutes, though its metabolic effects persist significantly longer due to downstream cellular activation

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J Neurosci 18:52255233 Bigford GE, Del Rossi G (2014) Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders

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